5.7.750 Microsoft bounce: unregistered domain blocked
What 5.7.750 means
Exchange Online blocked a high volume of mail sent from a domain that is not registered or validated in your Microsoft 365 tenant.
Message text
Client blocked from sending from unregistered domain
Common causes of 5.7.750
- Large volume of mail sent from a domain that is not an accepted domain in the tenant
- Incorrectly configured connector (less common)
How to fix 5.7.750
- Add and validate every domain you send from in Microsoft 365, then send again.
- Check connectors and look for compromised accounts, as the page advises, if the volume was not expected.
Check your domain
Read the headers of a bounced messageRuns in your browser; nothing is uploaded.
Get your domain's deliverability score
Have the full bounce message? Paste it into the bounce code lookup and it will match the code and the provider for you. Open the bounce code lookup.
How to read 5.7.750
The second part, 5.7.750, is an enhanced status code (RFC 3463 §2) written class.subject.detail. Class 5 is a Permanent failure (5xx): the command was rejected and the sender should not repeat it unchanged (RFC 5321 §4.2.1; RFC 3463 §2).. Subject 7 is security or policy: authentication, authorization or policy refused the message. The detail number refines the subject, and providers may define details of their own, which is why one code can read differently at Gmail, Microsoft and Yahoo.
Do not keep resending the same message: a permanent failure repeats until the cause is fixed. Correct the cause, then send a new message.
Official source: learn.microsoft.com. Last verified 2026-10-20.
Related guides
- How to create an SPF record (syntax and examples)
- How DKIM works and how to publish a DKIM record
- How to set up a DMARC record, from p=none to p=reject
Related codes
- 5.7.0 SMTP: security status
- 5.7.1 SMTP: delivery not authorized
- 5.7.23 SMTP: SPF validation failed
- 5.7.25 SMTP: reverse DNS failed
- 5.7.26 SMTP: authentication failed
- 5.7.27 SMTP: sender has null MX
FAQ
What does 5.7.750 mean?
Exchange Online blocked a high volume of mail sent from a domain that is not registered or validated in your Microsoft 365 tenant. This is a permanent failure.
How do I fix 5.7.750?
Add and validate every domain you send from in Microsoft 365, then send again. Check connectors and look for compromised accounts, as the page advises, if the volume was not expected.
Is 5.7.750 permanent, and should I retry?
5.7.750 is a permanent failure, so retrying the same message will fail again. Fix the cause first, then send a new message.