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5.1.0 Microsoft bounce: sender denied

Permanent failure (5.1.0): the receiving system will not accept this message as sent, so resending it unchanged will not help. Fix the cause first.

What 5.1.0 means

Exchange Online could not resolve the recipient or sender address for this message, so it returned a sender-denied NDR.

Message text

Sender denied

Common causes of 5.1.0

How to fix 5.1.0

  1. Check the recipient address and send the message again.
  2. Pick the recipient from the address book rather than an old saved copy of the message.

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How to read 5.1.0

The second part, 5.1.0, is an enhanced status code (RFC 3463 §2) written class.subject.detail. Class 5 is a Permanent failure (5xx): the command was rejected and the sender should not repeat it unchanged (RFC 5321 §4.2.1; RFC 3463 §2).. Subject 1 is addressing: a problem with the recipient or sender address. The detail number refines the subject, and providers may define details of their own, which is why one code can read differently at Gmail, Microsoft and Yahoo.

Do not keep resending the same message: a permanent failure repeats until the cause is fixed. Correct the cause, then send a new message.

Official source: learn.microsoft.com. Last verified 2026-10-20.

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FAQ

What does 5.1.0 mean?

Exchange Online could not resolve the recipient or sender address for this message, so it returned a sender-denied NDR. This is a permanent failure.

How do I fix 5.1.0?

Check the recipient address and send the message again. Pick the recipient from the address book rather than an old saved copy of the message.

Is 5.1.0 permanent, and should I retry?

5.1.0 is a permanent failure, so retrying the same message will fail again. Fix the cause first, then send a new message.

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